When choosing which testosterone therapy is appropriate for a patient, considerations are convenience of administration, the pharmacokinetics of the formulations, and the patient's preferences, needs, and lifestyle. Chronic hypogonadism has a negative impact on quality of life; inconsistent adherence causes nonphysiologic serum testosterone levels and may impair sexual function; and testosterone therapy is long-term. For these reasons, patient adherence to the medication regimen is also a critically important consideration.




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Seftel AD, Hellstrom WJG. Clinical consult. TestosteroneUpdate website. Posted May 29, 2009. http://testosteroneupdate.org/20090529ClinicalConsult.php. Accessed March 20, 2010.
1. Which factor(s) should be considered when deciding which testosterone formulation to prescribe?
Patient's preferences and needs
Patient's likely adherence to a given medication regimen
Pharmacokinetics of the formulations
All of the above